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Targeted next generation sequencing identifies somatic mutations in a cohort of Egyptian breast cancer patients

Mã tin: 1018
Ngày đăng: 05/02/2023
Gian hàng: mangyte
Khu vực: Hà nội
Giá: Liên hệ

Breast cancer (BC) incidence is progressively increasing in Egypt. However, there is insufficient knowledge of the acquired somatic mutations in Egyptian BC patients which limit our understanding of its progression. To the best of our knowledge, this is the first Egyptian cohort to sequence a multiple-gene panel of cancer related genes on BC patients. Four hundred and nine cancer related genes were sequenced in 46 fresh breast tumors of Egyptian BC patients to identify somatic mutations and their frequencies.TP53 and PIK3CA were the most top two frequently mutated genes.

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Nguồn: https://tailieu.vn/doc/targeted-next-generation-sequencing-identifies-somatic-mutations-in-a-cohort-of-egyptian-breast-canc-2246915.html